From: Parameter estimation in systems biology models using spline approximation
Parameters | Nominal value | Estimated parameters | |||
---|---|---|---|---|---|
 |  | Noise level 0% | Noise level: 2.5% | Noise level: 5% | Noise level: 10% |
k 1 | 1 | 0.9957 | 1.0150 | 1.1105 | 1.6037 |
k 2 | 1.6 | 1.5989 | 1.4138 | 1.5187 | 1.0315 |
k 3 | 0.05 | 0.0500 | 0.0528 | 0.0392 | 0.0381 |
k 16 | 0.4 | 0.4002 | 0.4440 | 0.3959 | 0.9331 |
k 34 | 0.04 | 0.0400 | 0.0414 | 0.0337 | 0.0215 |
k 43 | 0.01 | 0.0100 | 0.0142 | 0.0090 | 1.45e-10 |
k 61 | 0.3 | 0.2985 | 0.3432 | 0.2847 | 0.8185 |
k 67 | 0.7 | 0.6999 | 0.4535 | 1.3974 | 1.3108 |
k 76 | 0.1 | 0.0999 | 0.0457 | 0.2446 | 0.1845 |
k 23 | 0.3 | 0.1219 | 0.4134 | 0.6132 | 0.5579 |
k 25 | 0.9 | 0.1785 | 0.7063 | 0.8291 | 0.7874 |
k 28 | 0.06 | 0.0601 | 0.0669 | 0.0222 | 0.0198 |
k 39 | 0.07 | 0.0700 | 0.0549 | 0.0520 | 0.0334 |
k 96 | 0.01 | 0.0100 | 0.0441 | 0.0002 | 4.55e-14 |
a | 0.04 | 0.0400 | 0.1257 | 0.1260 | 0.1265 |
J 11 | 0.5 | 0.4992 | 0.5612 | 0.4252 | 0.6523 |
J 12 | 5 | 5.0025 | 4.8940 | 4.6892 | 5.4021 |
J 15 | 0.001 | 0.0051 | 0.0011 | 0.0010 | 0.0011 |
J 18 | 0.6 | 0.5990 | 0.7253 | 0.8014 | 1.1290 |
J 61 | 5 | 5.2581 | 4.1474 | 6.4585 | 7.2003 |
J 62 | 8 | 8.0088 | 29.734 | 39.403 | 41.408 |
J 65 | 6 | 5.9222 | 8.7804 | 9.3474 | 7.8076 |
J 68 | 7 | 6.9916 | 31.979 | 25.125 | 36.795 |
J 13 | 0.002 | 0.0050 | 0.0013 | 0.0016 | 2.61e-14 |
J 63 | 2 | 1.9740 | 1.4726 | 0.4203 | 19.871 |
K m1 | 0.5 | 0.4905 | 0.5267 | 0.5601 | 0.0410 |
K m2 | 4 | 3.9985 | 4.0482 | 4.1061 | 3.8495 |
K m4 | 0.3 | 0.2999 | 0.2838 | 0.2735 | 0.2338 |
K m9 | 0.005 | 0.0054 | 3.69e-5 | 2.03e-5 | 3.88e-6 |
K p | 0.05 | 0.0499 | 0.0452 | 0.0496 | 0.0311 |
Ï• 1 | 0.005 | 0.0044 | 0.0057 | 0.0041 | 0.0073 |
Ï• 2 | 0.1 | 0.0999 | 0.0920 | 0.0983 | 0.0693 |
Ï• 3 | 0.023 | 0.0230 | 0.0261 | 0.0164 | 0.0152 |
Ï• 4 | 0.03 | 0.0300 | 0.0279 | 0.0253 | 0.0218 |
Ï• 5 | 0.01 | 0.0100 | 0.0098 | 0.0101 | 0.0101 |
Ï• 6 | 0.06 | 0.0606 | 0.0627 | 0.0608 | 0.1518 |
Ï• 7 | 0.04 | 0.0401 | 0.0436 | 0.0404 | 0.0788 |
Ï• 8 | 0.06 | 0.0600 | 0.1546 | 0.0024 | 0.0260 |
Ï• 9 | 0.05 | 0.0500 | 0.0025 | 0.0439 | 0.0276 |
J | Â | 7.5399e-6e | 0.0005 | 0.0009 | 0.0025 |