Figure 14From: Computational modelling elucidates the mechanism of ciliary regulation in health and diseaseKey ciliary ion channels conductivity dependence on membrane potential. The overall ciliary excitability properties are due to the unique combination of ion channel conductivity dependence on membrane potential. The normalised ion channel conductivities are shown for Ca2+ currents v(V), K+ currents ν K + ( V ) , hyperpolarisation-induced currents vh(V), and the cilia-to-cell currents vt(V). The hyperpolarisation and cilia-to-cell currents are activated by membrane hyperpolarisation, whereas the activation of Ca2+ and K+ channels takes place under depolarised conditions.Back to article page