Figure 4From: Computational modelling elucidates the mechanism of ciliary regulation in health and diseaseThe predicted probabilities for Ca2+ channels to be in the open state. The indirect Ca2+-mediated inhibition of Ca2+ channels via a Ca2+-sensor protein, Cac0, is shown for a range of Ca2+-binding protein concentrations. The higher levels of Ca2+-sensor contributes to a greater degree of inhibition, although the general mechanism remains the same.Back to article page