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Figure 6 | BMC Systems Biology

Figure 6

From: Computational modelling elucidates the mechanism of ciliary regulation in health and disease

Figure 6

The membrane potential effects on Ca2+ current under fixed voltage. (A) The relationship between membrane potential and intraciliary Ca2+ concentration is shown under voltage clamp conditions. (B) The inward current amplitude dependence as a function of a fast shift in the holding membrane potential. Calculations were performed for different concentrations of Ca2+ sensor protein, CaC0. The model predicts qualitatively similar responses for a relatively wide range of Cac0 concentrations.

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