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Table 2 Validation of biomarkers based on over-expression in published OC microarray datasets available in databases such as CleanEx and Oncomine

From: In Silico discovery of transcription factors as potential diagnostic biomarkers of ovarian cancer

 

TFs regulating all 323 genes

TFs regulating Estrogen controlled sub-set of genes

 

Out of top ranked 17

Out of top ranked 17

CleanEX

1

2

Oncomine

Fold change > = 2

Fold change > = 1.5

Fold change > = 2

Fold change > = 1.5

TFs found

8

10

6

6

Total over-expressed TFs

9

11

8

8