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Figure 4 | BMC Systems Biology

Figure 4

From: How neurons migrate: a dynamic in-silico model of neuronal migration in the developing cortex

Figure 4

Lis1 reduced activity experiment. A. In-silico migration in Lis1-defective simulations. B. Histology of neuronal migration in the cortex of a Lis1 RNAi in mice (reproduced with permission from [24]). C. Distribution of multipolar (blue) and bipolar (red) neurons over time (averaged over 10 different simulations). D. Zone occupancy as function of time (VZ/SVZ blue), IZ (green) and CP (red) (averaged over 10 different simulations).

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