How neurons migrate: a dynamic in-silico model of neuronal migration in the developing cortex

BMC Systems Biology

Table 1 Bipolar migration under varying expression levels of Lis1 and DCX regulators

Lis1	DCX	Bipolar Migration (mouse cortex)	Bipolar Migration (rat cortex)
Reduced	Reduced	Reduced	Abnormal
Reduced	Normal	Reduced	Abnormal
Reduced	Over	Normal	Abnormal (*)
Normal	Reduced	Normal	Abnormal
Normal	Normal	Normal	Normal
Normal	Over	Normal/Enhanced (*)	Enhanced

Bipolar morphology under different expression levels of DCX and Lis1 in the mouse and rat cortex. The asterisk symbol indicates predicted morphologies.

ISSN: 1752-0509