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Figure 7 | BMC Systems Biology

Figure 7

From: Astrocyte - neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions - in silico study supported by in vitro expression data

Figure 7

The kinetics of glucose utilization, lactate production and ATP synthesis in neurons and astrocytes according to the ANLSH under hypoxic condition (Initial glucose concentration in the blood = 4.56 mM, oxygen concentration = 0.35 mM); (a) Glucose consumption in astrocytes (Ac); (b) Lactate kinetics in neurons (Nc), astrocytes (Ac) and the extracellular matrix (e); (c) ATP production in astrocyte cytoplasm (Ac); (d) Mitochondrial ATP production in neurons (Nm); inset shows a longer simulation (500 min).

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BMC Systems Biology

ISSN: 1752-0509

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