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Figure 8 | BMC Systems Biology

Figure 8

From: Astrocyte - neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions - in silico study supported by in vitro expression data

Figure 8

The kinetics of glucose utilization, lactate production and ATP synthesis in neurons and astrocytes according to the ANLSH for starvation conditions (Initial glucose concentration in the blood = 1 mM (glucose starvation), oxygen concentration = 7 mM); (a) Glucose consumption in astrocytes (Ac); (b) Lactate kinetics in neurons (Nc), astrocytes (Ac) and the extracellular matrix (e); (c) ATP production in astrocyte cytoplasm (Ac); (d) Mitochondrial ATP production in neurons (Nm).

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