Figure 4From: Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenasePrediction of co-variance. (A) Loadings plot of principal component analysis indicates strong co-variance between Grx1 and Prx2. (B) Off-target "modulation" of Prx2 by variable silencing of Grx1 in epi-allelic cell lines shows co-variance of Grx1 and Prx2 levels in three of four cell lines.Back to article page