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Table 5 Pathway database content statistics of core metabolic processes

From: Critical assessment of human metabolic pathway databases: a stepping stone for future integration

  Number of (percentage of total)
Database Genes EC numbers Metabolites Reactions
BiGG 957 (64%) 558 (87%) 1041 (70%) 1301 (50%)
EHMN 1221 (49%) 707 (75%) 1924 (72%) 2180 (56%)
HumanCyc 832 (23%) 503 (41%) 847 (50%) 815 (46%)
KEGG 1291 (84%) 619 (85%) 1190 (77%) 1308 (80%)
Reactome 413 (36%) 279 (78%) 532 (54%) 511 (43%)
  1. Genes: counts based on the internal database identifiers and including genes encoding for a component of a protein complex as separate entities. EC numbers: only fully specified EC numbers are counted. Metabolites: counts based on the internal database identifiers and including instances of metabolite classes for HumanCyc and members of sets for Reactome. Reactions: if reactions only differ in direction and/or compartments they are counted as one.