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Table 5 Pathway database content statistics of core metabolic processes

From: Critical assessment of human metabolic pathway databases: a stepping stone for future integration

 

Number of (percentage of total)

Database

Genes

EC numbers

Metabolites

Reactions

BiGG

957 (64%)

558 (87%)

1041 (70%)

1301 (50%)

EHMN

1221 (49%)

707 (75%)

1924 (72%)

2180 (56%)

HumanCyc

832 (23%)

503 (41%)

847 (50%)

815 (46%)

KEGG

1291 (84%)

619 (85%)

1190 (77%)

1308 (80%)

Reactome

413 (36%)

279 (78%)

532 (54%)

511 (43%)

  1. Genes: counts based on the internal database identifiers and including genes encoding for a component of a protein complex as separate entities. EC numbers: only fully specified EC numbers are counted. Metabolites: counts based on the internal database identifiers and including instances of metabolite classes for HumanCyc and members of sets for Reactome. Reactions: if reactions only differ in direction and/or compartments they are counted as one.