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Table 3 Centrality ranks for the HD network.

From: Inferring pleiotropy by network analysis: linked diseases in the human PPI network

  nD   nCC   nBC   TI3   TO30.01   TO30.005
P62993 31.11 P62993 46.54 P62993 37.39 P62993 277.53 P62993 8066 P12931 20642
P63104 19.80 P12931 44.47 P63104 26.06 P63104 204.08 P63104 7107 P62993 19760
P06241 16.21 P22681 44.31 P12931 13.57 P06241 117.74 P12931 6893 P06241 19595
P12931 14.67 P00533 43.76 P17252 13.52 P12931 100.73 P06241 5541 P63104 18434
P17252 10.32 P06241 42.78 P49407 13.33 P49407 100.05 P17252 4025 P49407 16818
P49407 10.32 Q13813 42.67 P06241 12.97 P62736 95.47 P28482 2338 P62736 16177
P62736 9.81 P00519 42.01 P62736 11.69 P17252 90.13 P07948 2104 P17252 15588
P28482 8.97 P21333 41.75 P02768 10.94 P02768 86.69 P62736 1875 P28482 13598
P27361 7.43 P63104 41.74 P28482 9.30 P28482 66.61 P27361 1800 P22681 13337
P02768 7.19 P17252 41.69 P22681 5.71 P27361 52.43 P49407 1661 P07948 12088
P22681 5.42 P07355 41.48 P27361 5.35 Q03135 36.93 P22681 1634 P27361 9436
P07948 5.37 P61978 41.45 Q03135 4.67 P22681 36.86 P51681 1280 Q03135 9271
Q03135 4.58 P28482 41.39 P07948 3.38 P07948 35.10 P05129 955 P41240 7227
P41240 2.80 Q02156 40.82 P09471 2.25 Q99962 18.32 P09471 925 P05129 3574
P05129 2.43 P29353 40.77 Q99962 2.08 P05106 18.32 O15303 875 P05106 3532
P05106 2.38 P07900 40.70 P05106 2.02 P09471 18.02 O15492 875 P98082 1867
Q99962 2.01 P62988 40.68 P41240 1.44 P05129 17.42 O15539 875 P51681 1828
P09471 1.54 O14939 40.64 P00533 0.97 P41240 15.68 O15552 875 Q99962 1730
P13500 1.03 P43405 40.52 Q9UBS5 0.89 P48745 6.64 O43566 875 P18031 1574
O14788 0.79 Q06124 40.51 P18545 0.84 P13500 6.11 O43665 875 P00533 1521
P80098 0.79 Q07889 40.51 P13500 0.84 P80098 5.16 O76081 875 O15492 1504
P48745 0.61 P06396 40.29 P05129 0.82 P54646 5.08 P04899 875 P04004 1471
P00533 0.51 P56945 40.28 P06396 0.80 O14788 4.81 P08913 875 P49757 1471
P80075 0.51 P06213 40.19 P48745 0.76 P80075 2.53 P16473 875 P16284 1440
P54646 0.47 O43707 40.16 P80098 0.69 Q99616 2.42 P18545 875 P29353 1440
Q99616 0.47 Q05655 40.06 P61981 0.69 P00533 2.14 P18825 875 Q05397 1440
P29353 0.42 P49407 40.01 P11532 0.67 P29353 1.58 P30542 875 Q99704 1440
P06213 0.37 Q15746 40.00 O14788 0.64 P17302 1.51 P32302 875 P31751 1308
P17302 0.37 P23528 39.93 Q92616 0.62 P43405 1.44 P34998 875 P02751 1297
P43405 0.37 Q00839 39.93 P02751 0.59 P06213 1.43 P35372 875 P06756 1297
  1. The rank of the most central 30 nodes in the HD network, based on the six importance indices analyzed.