Network analysis of microRNAs and their regulation in human ovarian cancer

BMC Systems Biology

Table 1 Number of nodes in the networks of OC-associated elements NW1000 and NW5000

	NW1000	NW5000
miRNAs	162	162
miRNA targets (OC cancer genes)	131	131
Transcription factors	237	244
Transcription co-factors	140	140
Edges miRNA→ target	434	434
Edges TF → miRNA	5327	14720
Protein-protein-interactions	4382	4409
Total edges	10143	19563
Total nodes	651	658

The table shows the number of different nodes in the constructed networks. NW1000 concentrates on regulatory elements in the core promoter while NW5000 attempts to also include more distally located regulatory elements.

ISSN: 1752-0509