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Figure 3 | BMC Systems Biology

Figure 3

From: Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines

Figure 3

Gene expressions of two segment CNV association modules and one mutation association module. Top: From the top to bottom: segment 18 (chr 3p) CNV, ZIC1 expressions, MITF expressions, and expressions of passenger genes. Middle: From the top to bottom: segment 31 (chr 6q) CNV, HDAC2 expressions, TBP expressions, MYB expressions, and expressions of passenger genes. Bottom: From the top to bottom: TP53 mutation states and expressions of passenger genes. Passengers are ordered by their similarity to driver aberration profiles. The top row has the highest similarity. BR: breast cancers, CNS: brain tumors, CO: colorectal cancers, LE: leukemias, ME: melanomas, LC: lung cancers, OV: ovarian cancers, PR: prostate cancers, RE: renal cancers.

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BMC Systems Biology

ISSN: 1752-0509

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