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Table 2 False discovery rates of mRNA and microRNA association modules

From: Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines

mRNA modules:   
FDR evaluation driver type FDR
mean intra CNV 0.0259
mean inter CNV 0.0035
mean mutation 0.3467
mean methylation 0.4334
mean microRNA 0.2248
mean TF 0.2197
mean all 0.2353
99% intra CNV 0.0855
99% inter CNV 0.0899
99% mutation 0.4949
99% methylation 0.6322
99% microRNA 0.3109
99% TF 0.2815
99% all 0.3262
microRNA modules:   
FDR evaluation driver type FDR
mean intra CNV NA
mean inter CNV 0.0021
mean mutation 0.2535
mean methylation 0.4403
mean microRNA NA
mean TF 0.2857
mean all 0.2924
99% intra CNV NA
99% inter CNV 0.0455
99% mutation 0.3645
99% methylation 0.6379
99% microRNA NA
99% TF 0.3600
99% all 0.3943
  1. Mean: using the expected number of false positives to evaluate FDR. 99%: using the 99 percentile of the number of false positives to evaluate FDR. Intra CNV: intra-segment CNV. Inter CNV: inter-segment CNV. TF: transcription factor expressions. All: the FDR over all associations.
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BMC Systems Biology

ISSN: 1752-0509

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