|
index
|
reg
|
N
1
|
N
2
|
N
3
|
p-value
|
|---|
|
44
|
MITF
|
118
|
2023
|
23
|
0.0464
|
|
45
|
TBP
|
77
|
8009
|
56
|
5.3704 × 10-4
|
|
45
|
MYB
|
77
|
10684
|
65
|
0.0076
|
|
46
|
SREBF2
|
49
|
9755
|
36
|
0.1581
|
|
47
|
E2F3
|
31
|
8123
|
21
|
0.0989
|
|
47
|
NFYA
|
31
|
2170
|
3
|
0.8513
|
|
47
|
SRF
|
31
|
75
|
0
|
1.0
|
|
51
|
NFATC3
|
22
|
2170
|
5
|
0.2097
|
|
53
|
NFKB2
|
19
|
531
|
0
|
1.0
|
|
66
|
TP53
|
35
|
3576
|
16
|
0.0041
|
|
76
|
PAX8
|
61
|
5376
|
34
|
0.0014
|
|
78
|
HOXC13
|
19
|
5421
|
12
|
0.0164
|
|
79
|
PPARG
|
13
|
20
|
0
|
1.0
|
|
81
|
mir-96
|
121
|
636
|
11
|
0.0147
|
|
81
|
mir-106a
|
121
|
319
|
6
|
0.0463
|
|
81
|
mir-17
|
121
|
830
|
12
|
0.0379
|
|
81
|
mir-93
|
121
|
832
|
12
|
0.0385
|
|
81
|
mir-106
|
121
|
718
|
11
|
0.0323
|
|
82
|
mir-21
|
120
|
291
|
7
|
0.0093
|
|
83
|
SMAD3
|
338
|
10025
|
271
|
1.058 × 10-7
|
|
84
|
ERG
|
338
|
2231
|
67
|
0.0093
|
|
84
|
ELK4
|
338
|
2803
|
76
|
0.0518
|
|
84
|
NFATC1
|
338
|
10187
|
265
|
3.1517 × 10-5
|
|
84
|
RFX3
|
338
|
2751
|
75
|
0.0481
|
|
84
|
POU5F
|
338
|
379
|
18
|
0.0027
|
- Index: module index. Reg: the transcription factor or microRNA with putative targets. N1: number of passenger genes in a module. N2: total number of putative targets in human genes. N3: number of passenger genes containing the transcription factor binding motif. p-value: hyper-geometric p-value of enrichment. For modules with microRNAs as drivers, N2: number of putative targets of a microRNA. N3: number of passenger genes belonging to the putative targets of the microRNA.
