Central carbon metabolism of M. extorquens AM1. Precursors of biomass components are labeled with an asterisk (*). Some metabolites were duplicated on the map for clearer visualization, and are indicated with ". Cofactors used as substrate or products are indicated in blue and red, respectively. GA3P, glyceraldehyde-3-phosphate; 3PG, 3-phosphoglycerate; 2PG, 2-phosphoglycerate; PEP, phosphoenol-pyruvate; OAA, oxaloacetate; 3HBCOA, 3-Hydroxy-butyryl-Coenzyme A; E4P, D-erythrose-4-phosphate; AKG, α-ketoglutarate; SED7P, sedoheptulose-7-phosphate; cyt c red: reduced cytochrome c. Dotted arrows represent uncertain reactions.