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Table 3 Genes exhibiting consistent relationships with inferred regulatory influences between the Calu-3 model, macaque, and mouse response data.

From: Conserved host response to highly pathogenic avian influenza virus infection in human cell culture, mouse and macaque model systems

Symbol ID Description Macaquea Mouse
ABI3 NM_016428 ABI gene family, member 3 0.35  
MXD1 NM_002357 MAX dimerization protein 1 0.35 0.53
ALOX5 NM_000698 arachidonate 5-lipoxygenase 0.36  
COL4A3 NM_000091 collagen, type IV, alpha 3 (Goodpasture antigen) 0.36  
C1QTNF3 NM_181435 C1q and tumor necrosis factor related protein 3 0.38  
CH25H NM_003956 cholesterol 25-hydroxylase 0.38 0.86
FOS NM_005252 v-fos FBJ murine osteosarcoma viral oncogene homolog 0.39  
TNFSF13B NM_006573 tumor necrosis factor (ligand) superfamily, member 13b 0.40  
IL1R2 NM_004633 interleukin 1 receptor, type II 0.40 0.88
CD86 NM_006889 CD86 molecule 0.40 0.87
TNFAIP3 NM_006290 tumor necrosis factor, alpha-induced protein 3 0.41 0.70
ASCL2 NM_005170 achaete-scute complex homolog 2 (Drosophila) 0.41  
IRX4 NM_016358 iroquois homeobox 4 0.41  
BATF2 NM_138456 basic leucine zipper transcription factor, ATF-like 2 0.41 0.88
SCNN1G X87160 sodium channel, nonvoltage-gated 1, gamma 0.42  
PARP11 NM_020367 poly (ADP-ribose) polymerase family, member 11 0.42 0.83
CMTM2 NM_144673 CKLF-like MARVEL transmembrane domain containing 2 0.42  
ADM NM_001124 Adrenomedullin 0.43 0.77
PRSS12 NM_003619 protease, serine, 12 (neurotrypsin, motopsin) 0.44  
USP18 NM_017414 ubiquitin specific peptidase 18 0.48 0.94
PI3 NM_002638 peptidase inhibitor 3, skin-derived (SKALP) 0.48  
IL29 NM_172140 interleukin 29 (interferon, lambda 1) 0.54  
UPP1 NM_181597 uridine phosphorylase 1 0.57 0.84
INDO NM_002164 indoleamine-pyrrole 2,3 dioxygenase 0.58 0.90
LDHC NM_002301 lactate dehydrogenase C 0.58  
CXCL10 NM_001565 chemokine (C-X-C motif) ligand 10 0.58 0.96
RND1 NM_014470 Rho family GTPase 1 0.59 0.85
IFIT2 NM_001547 interferon-induced protein with tetratricopeptide repeats 2 0.60 0.97
IFIT1 NM_001548 interferon-induced protein with tetratricopeptide repeats 1 0.62 0.96
IFIT3 NM_001549 interferon-induced protein with tetratricopeptide repeats 3 0.64 0.97
ATF3 NM_004024 activating transcription factor 3 0.66 0.86
OASL NM_003733 2'-5'-oligoadenylate synthetase-like 0.67  
CCL4 NM_002984 chemokine (C-C motif) ligand 4 0.67 0.92
JUNB NM_002229 jun B proto-oncogene 0.68 0.66
MX2 NM_002463 myxovirus (influenza virus) resistance 2 0.69 0.90
XAF1 NM_017523 XIAP associated factor-1 0.70  
IL6 NM_000600 interleukin 6 (interferon, beta 2) 0.71 0.92
RSAD2 NM_080657 radical S-adenosyl methionine domain containing 2 0.89 0.85
OAS2 NM_016817 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.92 0.84
  1. a Xpred scores from Calu-3 model cross-predictions in macaque and mouse. Bold indicates statistical significance (p-value < 0.05)