Figure 11From: Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodiesEffect of tumor microenvironment on the response to the anti-VEGF treatment. The fold-change in free VEGF concentration following anti-VEGF treatment is predicted as a function of properties of the tumor microenvironment. A, Effect of neuropilin internalization. B, Effect of VEGF isoform-specific secretion.Back to article page