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Table 2 Kinetic constants for NRP2 interactions

From: Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies

  Measured parameters Model parameters
  Value Unit Value Unit
k on,V165,N 2 106 M-1 s-1 1.92 × 10-3 (pmol/cm3 tissue)-1 s-1
k c,V165 R2,N 2 3.1 × 1013 (mol/cm2)-1 s-1 2.02 × 10-2 (pmol/cm3 tissue)-1 s-1
k c,V165 N 2,R2 1014 (mol/cm2)-1 s-1 7.06 × 10-2 (pmol/cm3 tissue)-1 s-1
k c,R1,N 2 1014 (mol/cm2)-1 s-1 7.06 × 10-2 (pmol/cm3 tissue)-1 s-1
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