Two way clustering of plasma metabolomic profiles of non-HHT patients (N1-N5) and HHT patient (Pre1 and Post). All of the blood draws were taken when patients were fasting, except for NF5 which was a non-fasting profile for individual N5. The non-fasting profile is clearly distinguished from the other profiles. Also blood draws for the HHT patient prior to bevacizumab treatment (Pre1) is in a distinct branch from the other profiles. Note that the post-treatment profile (Post) for the HHT patient is concordant with the non-HHT individual's profiles.