3D PCC scatter plot showing correlations in analog signature gene expression among LPI, MPI, and HPI pathogenicity groups. Rather than using a single biological sample as an exemplar of a given pathogenicity (as in Figure. 3), all samples of a given pathogenicity were averaged together (using variance-weighted averages) and each average was used as a new exemplar. Samples (as data points) are colored following the legend in Figure. 1. Dots colored more lightly represent 2D projections of correlations for given pairs of pathogenicity groups.