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Table 2 Configurations for the GAL network variants modeled in this study

From: Modeling the evolution of a classic genetic switch

  Gene copy-number
Network GAL1 GAL2 GAL3 GAL4 GAL80 GAL1/3
1 0 1 0 1 1 1
2 0 1 0 1 1 2
3 0 1 0 1 2 2
4 0 1 0 2 1 2
5 0 1 0 2 2 2
6 0 1 1 1 1 1
7 0 1 1 1 2 1
8 0 1 1 2 1 1
9 0 1 1 2 2 1
10 0 2 0 1 1 2
11 0 2 0 1 2 2
12 0 2 0 2 1 2
13 0 2 0 2 2 2
14 0 2 1 1 1 1
15 0 2 1 1 2 1
16 0 2 1 2 1 1
17 0 2 1 2 2 1
18 1 1 0 1 1 1
19 1 1 0 1 2 1
20 1 1 0 2 1 1
21 1 1 0 2 2 1
22 1 1 1 1 1 0
23 1 1 1 1 2 0
24 1 1 1 2 1 0
25 1 1 1 2 2 0
26 1 2 0 1 1 1
27 1 2 0 1 2 1
28 1 2 0 2 1 1
29 1 2 0 2 2 1
30 1 2 1 1 1 0
31 1 2 1 1 2 0
32 1 2 1 2 1 0
33 1 2 1 2 2 0
  1. Evolutionary changes, such as the WGD, gene duplicate loss, and specialization of GAL1/3 to GAL1 and GAL3 connect these networks along evolutionary trajectories to S. cerevisiae (see Figure 4).