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Table 2 Configurations for the GAL network variants modeled in this study

From: Modeling the evolution of a classic genetic switch

 

Gene copy-number

Network

GAL1

GAL2

GAL3

GAL4

GAL80

GAL1/3

1

0

1

0

1

1

1

2

0

1

0

1

1

2

3

0

1

0

1

2

2

4

0

1

0

2

1

2

5

0

1

0

2

2

2

6

0

1

1

1

1

1

7

0

1

1

1

2

1

8

0

1

1

2

1

1

9

0

1

1

2

2

1

10

0

2

0

1

1

2

11

0

2

0

1

2

2

12

0

2

0

2

1

2

13

0

2

0

2

2

2

14

0

2

1

1

1

1

15

0

2

1

1

2

1

16

0

2

1

2

1

1

17

0

2

1

2

2

1

18

1

1

0

1

1

1

19

1

1

0

1

2

1

20

1

1

0

2

1

1

21

1

1

0

2

2

1

22

1

1

1

1

1

0

23

1

1

1

1

2

0

24

1

1

1

2

1

0

25

1

1

1

2

2

0

26

1

2

0

1

1

1

27

1

2

0

1

2

1

28

1

2

0

2

1

1

29

1

2

0

2

2

1

30

1

2

1

1

1

0

31

1

2

1

1

2

0

32

1

2

1

2

1

0

33

1

2

1

2

2

0

  1. Evolutionary changes, such as the WGD, gene duplicate loss, and specialization of GAL1/3 to GAL1 and GAL3 connect these networks along evolutionary trajectories to S. cerevisiae (see Figure 4).