A new computational method to split large biochemical networks into coherent subnets

BMC Systems Biology

Table 1 Efficacy values

	Flavonoid	M. pneumon	Arabid. t.	M. musculus
S-matrix size	137 × 117	189 × 229	1468 × 1348	2016 × 2158
p-value	2.1	2.8	7.2	7.6
Threshold	High connectivity cutoff method
20	0	33	18	25
10	19	33	24	32
8	19	33	27	37
6	31	37	49	41
5	80	45	54	33
4	76	60	43	27
3	29	32	32	21
Netsplitter	Default automated externals and reincorporation
	88	85	70	48

Values are shown as percentages, and peak values highlighted in bold. The p-value increases with network size as described in the text.

ISSN: 1752-0509