From: Predicting the points of interaction of small molecules in the NF-κB pathway
Dataset | ROS interaction | Inhibits translocation | Interfering with DNA binding | Inhibits IKK activation | Inhibits IκB degradation or phosphorylation | Activates IκB degradation or phosphorylation |
---|---|---|---|---|---|---|
Training set 1 | 12 | 5 | 48 | 104 | 69 | 3 |
Test set 1 | 2 | 2 | 12 | 34 | 7 | 3 |
Training set 2 | 11 | 5 | 52 | 111 | 57 | 4 |
Test set 2 | 3 | 2 | 8 | 27 | 19 | 2 |
Training set 3 | 11 | 5 | 53 | 107 | 60 | 4 |
Test set 3 | 3 | 2 | 7 | 31 | 16 | 2 |
Training set 4 | 11 | 6 | 48 | 112 | 61 | 3 |
Test set 4 | 3 | 1 | 12 | 26 | 15 | 3 |
Training set 5 | 11 | 6 | 48 | 108 | 62 | 5 |
Test set 5 | 3 | 1 | 12 | 30 | 14 | 1 |