Source database | Information type | Current statistics | Level of curation | Updates/Version |
---|---|---|---|---|
BIND | Protein interaction Molecular complexes Pathways | 6256 Interactions | High throughput data submission and manually curated from literature | last public version 20.3.07 |
BioGrid | Protein interaction | 19 707 interactions | Manually curated from literature Different evidence codes | updated monthly |
BRENDA | Enzyme kinetics | 4 729 | Manually curated from literature | updated monthly |
ChEBI | Compound information | 15 367 | Curated from different data sources | updated weekly |
Comparative Toxicogenomics Database (CTD) | Compound-gene, Compound-disease and Gene-disease relationships | 259 898 relations | Manually curated from literature | updated monthly |
EntrezGene | Gene functional information | 80 793 human, mouse and rat genes | Curated information integrated from different databases, based on RefSeq genomes | updated weekly |
Enzyme | Enzyme related functional information | 4 833 | Manually curated from literature | updated weekly |
GEO | Functional genomics data (expression, ChIP-chip etc.) | >400 000 individual experiments | User submission | updated weekly |
IntAct | Protein interaction | 21 584 binary interactions | Literature curation User submission | updated weekly |
KEGG | Pathways | 418 pathways | Manually curated from literature | updated monthly |
LIGAND | Compound information | 15 185 | Manually curated from the published literature | updated monthly |
MIPS Mammalian | Protein Interaction | 410 interactions | Manually curated from literature | current release 31.10.07 |
OMIM | Gene - disease relations | 20 823 | Curated from literature | updated weekly |
Pfam | Protein family information | 10 340 families | Manually curated from sequence alignments | 23.0 |
ProLinks | Interaction | >1.4 million | Automatic inference | last release 18.10.04 |
PubChem | Compound information | >26 million | Automatic collection | updated weekly |
PubMed | Literature abstracts | >19 million | Automatic collection with manual curation | updated weekly |
Reactome | Interactions and pathways | >600 pathways, >24 000 Inteactions | Manual curation | updated monthly |
RefSeq | DNA and protein sequences | >11 million | Automatic processing and manual curation | updated weekly |
Unigene | Transcript sequences | >2 million | User submission followed by automatic clustering | updated monthly |
UniProt | Protein sequences | >10 million | Automatic processing, Swissprot subsection manual curation | updated bi-weekly |