Figure 3

Maximum genotype distances and robustness depend strongly on the number of superessential reactions and the sizes of minimal metabolic networks. (A) Average maximum genotype distance for metabolic networks of different sizes and subject to different environmental demands after random walks of 10 000 accepted reaction changes. (B) Robustness of random metabolic networks with different sizes and subject to different environmental demands. Each data point is an average over 200 random walks (20 random walks for 10 different sets of environmental demands with the same number S of sulfur sources).