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Figure 1 | BMC Systems Biology

Figure 1

From: A stem cell niche dominance theorem

Figure 1

Stem cell model. Without loss of generality to the result of our analysis, we assume a simple stem cell model with three kinds of cells and where stem and transient cells can divide symmetrically and asymetrically. Through cell division lineages are generated. The stemness of the lineages is assessed with respect to their capacity (propensity) to contribute towards a specific future development (fate) of the tissue. A lineage that generates a long and wide tree would have a much higher stemness than a thin and short branch.

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