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Table 3 Main topological parameters of capacitation network after "actin polymerization" node removal

From: The role of actin in capacitation-related signaling: an in silico and in vitro study

Parameter

Value

N° nodes

152

N° edges

196

Clustering coefficient

0.056

Diameter

12

Averaged n° neighbours

2.566

Char. path length

6.071

Degree distribution

b = -1.563

 

r = 0.809 R2 = 0.898

  1. The number of nodes represent the total number of molecules involved, the number of edges represents the total number of interaction found, the clustering coefficient is calculated as C I = 2n I/k(k-1), where n I is the number of links connecting the k I neighbours of node I to each other, the network diameter is the largest distance between two nodes, the Averaged n° neighbours represent the mean number of connection of each node, the Char. path length gives the expected distance between two connected nodes.