Method procedure. First, we obtained the PPANs for each of the two species from STRING database. Secondly, a BLAST bi-directional procedure is executed for both species. Then, a NetworkBLAST analysis using the PPANs and BLAST best hits results is executed and conserved functional modules between the two species are obtained. The GO terms for each protein node in the conserved modules are assigned using GOA files for each species. Proteins with no entry in GOA file remain unannotated.