Figure 4From: A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stressMean PoP of a number of elements in selected mutants. The gene was turned o after the first million of steps. A: PoP of protoporphyrin-IX when the gene HEM15 is turned o, B: superoxide anion and hydroxyl radical when the gene SOD1 is set to "OFF", C-F: PoP of glutamate, cysteine and glutathion C) when ACO1 is set to "OFF". Cysteine reached zero at steady-state, D: ACO1 is set to "OFF" and a source of glutamate is added, E: HEM1 is set to "OFF", F: HEM1 is set to "OFF" and a source of glutamate is added.Back to article page