Table 1 Parameter values used in simulations
From: Theoretical basis of the community effect in development
Parameter | Reaction | Parameter value (sec -1) | t0.5(approx.) |
|---|---|---|---|
α 1 | Binding of transcriptional activator to promoter | 1.93 × 10 -4 | 1 hr |
α 2 | Dissociation of transcriptional activator from promoter | 3.47 × 10 -2 | 20 sec |
β | Transcription | 1.16 × 10 -2 | 1 min |
γ | Translation | 2.31 × 10 -2 | 30 sec |
δ a , δ b , δ c , δ d | Degradation/disappearance of proteins | 3.47 × 10 -4 | 33 min |
δ m | Degradation of mRNA | 1.16 × 10 -3 | 10 min |
κ | Exocytosis | 3.85 × 10 -4 | 30 min |
ε | 'Communication' by extracellular factor | 2.31 × 10 -6 or 5.78 × 10 -7 | 83 or 333 hrs |