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Figure 5 | BMC Systems Biology

Figure 5

From: DomainRBF: a Bayesian regression approach to the prioritization of candidate domains for complex diseases

Figure 5

ROC curves of the leave-one-out cross-validation experiments on shuffled data. (A) Results for random controls with domain-domain interactions shuffled. (B) Results for linkage intervals with domain-domain interactions shuffled. (C) Results for genome-wide scan with domain-domain interactions shuffled. (D) Results for random controls with known domain-phenotype associations shuffled. (E) Results for linkage intervals with known domain-phenotype associations shuffled. (F) Results for genome-wide scan with known domain-phenotype associations shuffled. (G) Results for random controls with phenotype similarity profiles shuffled. (H) Results for linkage intervals with phenotype similarity profiles shuffled. (I) Results for genome-wide scan with phenotype similarity profiles shuffled. The small domain-domain interaction network composed of the PDB part of the DOMINE database and the diffusion kernel are used to obtain the results.

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