Figure 3

Differential expression of gene in PKD and control animals. Heatmap was produced using simultaneous clustering of rows and columns of the data matrix using complete linkage algorithm and a euclidean distance metric. Prior to clustering, values were transformed to zero (row-wise) mean and unit (row-wise) variance. The gene clustering tree is shown on the left and the sample clustering tree is shown on the top. The samples are clustering broadly into two groups, wild type (WT) and PKD. The color scale shown at the right illustrates the relative expression level of the indicated gene across all samples: red denotes expression > 0 and green denotes an expression < 0. Genes shown here are from mRNA microarrays.