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Table 4 Top 50 differentially regulated genes common between our mouse and human ADPKD data from Song et al. [29]

From: Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

Down-regulated

Up-regulated

Gene name

Mouse

Human

Gene name

Mouse

Human

Abcb4

371.51

1.90

Adcy7

2.63

2.38

Acot2

4.81

1.81

Amph

218.83

2.34

Acox2

2.70

1.97

Arhgap10

2.61

2.43

Aldh8a1

2.37

91.29

Asph

3.96

2.84

Apom

2.22

18.96

Bcat1

15.08

4.95

Apoo

4.00

2.45

Camsap1l1

10.96

2.21

Bhmt2

2.26

4.78

Ccdc109b

4.48

3.17

Casc1

10.94

2.84

Cdc42bpa

2.70

1.57

Cldn10

2.25

25.93

Eif3a

98.69

2.14

Cpn2

10.64

2.07

Emilin1

4.06

4.78

Cyp8b1

12.17

30.21

Ezh1

3.45

1.80

Dpep1

7.37

17.20

Fam98b

352.24

1.63

Enpp5

3.11

2.59

Foxp2

26.87

3.75

Enpp6

2.21

8.65

Gli2

4.39

4.29

Fam151a

3.21

6.02

Gramd1a

6.84

1.92

G6pc

11.06

4.88

Grem1

2.98

37.73

Gls

2.35

5.69

Ier2

2.67

3.25

Hgd

2.56

38.57

Jph2

39.24

1.85

Hrg

24.10

16.90

Klhl28

4.94

1.78

Itih2

6.35

2.45

Ltbp1

36.39

5.33

Kctd14

6.15

1.62

Mid1

2.59

2.51

Kng1

2.68

81.30

Nnmt

49.60

1.96

Larp5

7.00

1.57

Odf3b

13.13

1.56

Miox

28.27

20.49

Pcdh7

3.18

11.00

Napepld

2.10

2.65

Pcdh9

40.71

4.90

Napsa

3.60

10.05

Pdcl

75.38

1.71

Odz2

3.97

2.15

Pi4kb

2.90

1.75

Pck1

3.28

58.93

Pknox2

7.28

2.84

Picalm

4.93

1.71

Pml

5.69

1.65

Prap1

3.25

5.24

Pprc1

6.17

1.77

Prlr

2.31

13.73

Rab9b

55.23

2.42

Prodh2

5.34

5.45

Radil

2.92

2.18

Psen1

20.62

2.05

Rpl37

3.29

3.04

Pvalb

2.89

3.59

Sema4c

3.13

1.63

Qpct

2.34

2.20

Sept7

3.12

2.87

Rassf6

10.76

3.30

Setd7

21.09

2.57

Rgs3

5.14

2.01

Sfi1

4.63

1.67

Serpinf2

2.16

2.49

Sfxn3

14.28

2.60

Slc13a2

5.87

7.03

Slitrk5

7.02

14.33

Slc16a4

3.38

4.32

Smurf1

2.90

1.71

Slc26a7

2.82

26.10

St5

2.54

1.62

Slc2a9

4.28

11.81

Syne1

6.02

3.12

Slc4a1

3.62

2.57

Synj2

27.19

3.23

Slc5a10

8.43

11.22

Thg1l

2.91

1.69

Slc8a1

2.11

4.08

Tns1

2.66

1.75

Tbc1d4

4.20

1.66

Vps13b

6.39

1.76

Treh

2.66

2.29

Wfdc3

145.61

1.66

Trim15

235.85

1.97

Yy1

3.48

1.72

Ttr

6.52

1.93

Zbtb10

4.06

1.62

Umod

3.41

210.17

Zfhx4

2.87

4.19

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BMC Systems Biology

ISSN: 1752-0509

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