Characterizing the disease modules. (a) Histogram of the index of aggregation distribution for Parkinson's disease enriched sets of proteins randomly selected from a database. The arrow indicates the aggregation values for the enriched Parkinson's disease proteins set. The Venn diagram (b) showed the neurological diseases relationships between aging and psychiatric diseases, The Venn diagram (c) showing the neurological disease relationship with depression. (d) Peak representation of positively scored disease pairs category and MeSH disease pairs category. The common region indicates the similarity disease pairs between the two categories. The Venn diagram (e) shows the presences of biomarkers in biofluid and house keeping genes.