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Table 1 Biomarkers score

From: Systems biological approach on neurological disorders: a novel molecular connectivity to aging and psychiatric diseases

Disease Biomarkers (score)
Alzheimer's Disease APLP2 (4), NEU2 (1.4), PCDH11X (0.5), SUMF1 (0.5), TOMM40 (0.5)
Amyotrophic Lateral Sclerosis ALS2CR8 (0.5), DERL1 (0.5), FUS (1), HOPX (0.5), KIF1A (0.5), MOBKL2B(0.5), NIF3L1 (0.5), SCN7A (0.5), SEMA6A (1.4), SLC39A11(0.5), STRADB (0.5), SUSD1(0.5), UNC13A(0.5), ZFP64(0.5)
Angelman Syndrome ARID4A (1.4), ARID4B (0.5), MKRN3 (1), NDNL2 (0.5), NIPA2 (0.5), PHLDA2 (0.5), SLC9A6(0.5), TSPAN32 (0.5), TSSC4 (0.5)
Asperger Syndrome GPR172B (0.5)
Ataxia Telangiectasia DDX10 (1), HEPACAM (1.4), TCL1A (0.5)
Canavan Disease ASPA(0.5)
Dyslexia ARFGEF1 (0.5), CCPG1 (0.5), PDGFC (0.5)
Epilepsy TRAPPC10 (0.5)
Fatal Familial Insomnia CD68 (0.5)
Friedreich Ataxia ACO1 (0.5)
Huntington disease AKAP8L (0.5), ARFIP2 (0.5)
Korsakoff Syndrome TKTL1 (0.5)
Lambert-Eaton Myasthenic Syndrome RAPSN (0.5), SOX1 (0.5)
Major Depressive Disorder FKBP5 (1), PCLO (2)
Manic Depressive Psychosis TRPM2(0.5)
Multiple Sclerosis CSMD1 (0.5), FCGR1A (2), FCGR1B (2), FCGR2A (3.5), FCGR2B (5), FCGR2C (4.1), FCGR3A (4.1), FCGR3B (0.5), IFNB1 (0.5)
Multiple System Atropy AGTPBP1 (0.5), EXTL3 (0.5)
Parkinson's Disease CALB1(5), CSF1R (5), MT-CYB(0.5), CHAC1 (0.5), NPFF (0.5)
Pathologic gambling DNER (3.5)
Restless Legs Syndrome DMRT1 (0.5)
Schizophrenia AP3B2(2), HMBS (0.5), SETD2(1.4), ST6GAL2(3.5)
Septo-Optic Dysplasia LBX1 (1)
Stroke NINJ2(0.5), PROZ (0.5)
von Hippel-Lindau Disease TCHP (0.5)
  1. The biomarkers of 24 diseases were indicated along with their diagnostic score. The biomarkers that are shown to be specific to neurological and psychiatric diseases in comparison with GWAS database are indicated in bold.