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Figure 3 | BMC Systems Biology

Figure 3

From: A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes

Figure 3

Scheme of the model used in the simultaneous model verification. In contrast to the full model illustrated in Figure 1, this model contains lumped transport kinetics, which means, one import and one export rate for each metabolite, respectively. This transport simplification resulted from the local parameter sensitivity analysis (see Additional file 4 - Analysis of parameter sensitivity and following model reduction procedure).

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