Skip to main content
Figure 6 | BMC Systems Biology

Figure 6

From: A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer

Figure 6

Epigenetic mechanisms in drug-resistant cells. Epigenetic mechanisms in ERα regulatory network in MCF7-T cell: 1 high basal gene expression in MCF7-T cells; 2 hypermethylation from MCF7 cells to MCF7-T cells; 3 hypomethylation from MCF7 cells to MCF7-H cells; 4 high basal methylation level in the MCF-T cells; 5 high H3K27/H3K4 ratio; and 6 unknown mechanisms. (A) The distribution of non-responsive mechanisms in ERα regulatory network in MCF7-T cell. (B) The overlap among 5 non-responsive mechanisms.

Back to article page
\