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Table 1 Gene Ontology Analysis of Estrogen Targets

From: A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer

ERα Target Mechanism 4 hour after E2 Stimulation 24 hour after E2 Stimulation
  Functional Category P-value Range N Functional Category P-value Range N
Genomic Gene Expression 2E-6 - 9E-3 26 Cellular Growth 4E-7 - 1E-2 96
  Cell Morphology 4E-6 - 1E-2 15 Cell Cycle 2E-6 - 1E-2 37
  Cellular Growth 3E-5 - 1E-2 37 Cell Death 4E-5 - 1E-2 70
  Cellular Development 5E-5 - 1E-2 22 Cellular Movement 5E-5 - 1E-2 46
  Cell Cycle 1E-4 - 1E-2 21 Cellular Development 6E-5 - 1E-2 48
Non-genomic RNA Post-Transcription 5E-6 - 4E-2 5 DNA Replication, Recombination, and Repair 1E-9 - 3E-2 62
  Modification      
  Cellular Development 8E-4 - 5E-2 2 Cell Cycle 1E-9 - 3E-2 70
  DNA Replication, Re-combination, and Repair 1E-3 - 4E-2 6 RNA Post-Transcription Modification 6E-6 - 2E-2 16
  Cellular Growth 1E-3 - 4E-2 8 Post-Transcription 5E-4 - 3E-2 15
  Amino Acid Metabolism 5E-3 - 5E-2 2 Modification Cellular Assembly and Organization 6E-4 - 3E-2 37
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