Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions

Table 1 Domain genetic interactions with top ten highest E scores.

E score	Prob.	Domain_a	Domain_a Pfam ID	# of Yeast proteins with domain_a	Domain_b	Domain_b Pfam ID	# of Yeast proteins with domain_b	# of GI
67.48	0.46	PF00225	Kinesin	6	PF01920	Prefoldin_2	4	11
65.59	0.72	PF01302	CAP_GLY	4	PF01920	Prefoldin_2	4	12
63.31	0.32	PF00022	Actin	9	PF01920	Prefoldin_2	4	11
41.73	0.025	PF00071	Ras	24	PF00071	Ras	24	13
39.53	0.036	PF00400	WD40	87	PF01920	Prefoldin_2	4	14
38.41	0.12	PF00071	Ras	24	PF04893	Yip1	3	8
36.53	0.027	PF00069	Pkinase	114	PF01920	Prefoldin_2	4	17
35.15	0.35	PF00225	Kinesin	6	PF02996	Prefoldin	3	6
33.16	0.80	PF01920	Prefoldin_2	4	PF03114	BAR	2	7
31.20	0.013	PF00022	Actin	9	PF00069	Pkinase	114	17

ISSN: 1752-0509