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Table 2 Predicted new synthetic lethal genetic interactions with probability greater than 0.9

From: Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions

Protein 1 Name Protein 1 Annotation Protein 2 Name Protein 2 Annotation Probability
MYO4 type V myosin motors DYN1 Cytoplasmic heavy chain dynein 0.9895
RPO21 RNA polymerase II largest subunit BRF1 TFIIIB B-related factor 0.9816
DST1 General transcription elongation factor TFIIS RET1 Second-largest subunit of RNA polymerase III 0.9797
STO1 Large subunit of the nuclear mRNA cap-binding protein complex RPA190 RNA polymerase I subunit 0.9586
STO1 Large subunit of the nuclear mRNA cap-binding protein complex RPO21 RNA polymerase II largest subunit 0.9586
DST1 General transcription elongation factor TFIIS RPA135 RNA polymerase I subunit A135 0.9570
BNR1 Formin, nucleates the formation of linear actin filaments DYN1 Cytoplasmic heavy chain dynein 0.9441
CEG1 Alpha (guanylyltransferase) subunit of the mRNA capping enzyme RPA190 RNA polymerase I subunit 0.9437
CEG1 Alpha (guanylyltransferase) subunit of the mRNA capping enzyme RPO31 RNA polymerase III subunit 0.9437
RPB5 RNA polymerase subunit RPA190 RNA polymerase I subunit 0.9437
RPB5 RNA polymerase subunit RPO31 RNA polymerase III subunit 0.9437
DST1 General transcription elongation factor TFIIS RPA190 RNA polymerase I subunit 0.9265
DST1 General transcription elongation factor TFIIS RPO31 RNA polymerase III subunit 0.9265
ARO1 Pentafunctional arom protein SPT16 Subunit of the heterodimeric FACT complex 0.9198
RET1 Second-largest subunit of RNA polymerase III SUA7 Transcription factor TFIIB 0.9035
BRF1 TFIIIB B-related factor RET1 Second-largest subunit of RNA polymerase III 0.9035
BRF1 TFIIIB B-related factor RPB2 RNA polymerase II second largest subunit 0.9035