Table 2 Predicted new synthetic lethal genetic interactions with probability greater than 0.9
Protein 1 Name | Protein 1 Annotation | Protein 2 Name | Protein 2 Annotation | Probability |
|---|---|---|---|---|
MYO4 | type V myosin motors | DYN1 | Cytoplasmic heavy chain dynein | 0.9895 |
RPO21 | RNA polymerase II largest subunit | BRF1 | TFIIIB B-related factor | 0.9816 |
DST1 | General transcription elongation factor TFIIS | RET1 | Second-largest subunit of RNA polymerase III | 0.9797 |
STO1 | Large subunit of the nuclear mRNA cap-binding protein complex | RPA190 | RNA polymerase I subunit | 0.9586 |
STO1 | Large subunit of the nuclear mRNA cap-binding protein complex | RPO21 | RNA polymerase II largest subunit | 0.9586 |
DST1 | General transcription elongation factor TFIIS | RPA135 | RNA polymerase I subunit A135 | 0.9570 |
BNR1 | Formin, nucleates the formation of linear actin filaments | DYN1 | Cytoplasmic heavy chain dynein | 0.9441 |
CEG1 | Alpha (guanylyltransferase) subunit of the mRNA capping enzyme | RPA190 | RNA polymerase I subunit | 0.9437 |
CEG1 | Alpha (guanylyltransferase) subunit of the mRNA capping enzyme | RPO31 | RNA polymerase III subunit | 0.9437 |
RPB5 | RNA polymerase subunit | RPA190 | RNA polymerase I subunit | 0.9437 |
RPB5 | RNA polymerase subunit | RPO31 | RNA polymerase III subunit | 0.9437 |
DST1 | General transcription elongation factor TFIIS | RPA190 | RNA polymerase I subunit | 0.9265 |
DST1 | General transcription elongation factor TFIIS | RPO31 | RNA polymerase III subunit | 0.9265 |
ARO1 | Pentafunctional arom protein | SPT16 | Subunit of the heterodimeric FACT complex | 0.9198 |
RET1 | Second-largest subunit of RNA polymerase III | SUA7 | Transcription factor TFIIB | 0.9035 |
BRF1 | TFIIIB B-related factor | RET1 | Second-largest subunit of RNA polymerase III | 0.9035 |
BRF1 | TFIIIB B-related factor | RPB2 | RNA polymerase II second largest subunit | 0.9035 |