Table 3 Enrichment of predicted interactions between pairs of E-MAPs
From: Improved functional overview of protein complexes using inferred epistatic relationships
Chromosome - RNA | ||||||
|---|---|---|---|---|---|---|
Positive | Negative | |||||
Dataset | Overlap | Enrichment | p-value | Overlap | Enrichment | p-value |
GO Process | 238 | 1.50 | 2.76E-12 | 393 | 1.66 | 9.55E-29 |
SGD Phenotype | 59 | 2.73 | 8.45E-12 | 135 | 4.19 | 9.35E-44 |
Positive Genetic | 20 | 23.82 | 7.29E-21 | 3 | 2.39 | 0.13 |
Synthetic Sick | 2 | 1.30 | 0.67 | 49 | 21.35 | 1.44E-46 |
Chromosome - Signalling | ||||||
Positive | Negative | |||||
Dataset | Overlap | Enrichment | p-value | Overlap | Enrichment | p-value |
GO Process | 56 | 1.39 | 5.98E-03 | 121 | 1.30 | 1.12E-03 |
SGD Phenotype | 10 | 1.40 | 2.50E-01 | 67 | 4.07 | 2.13E-22 |
Positive Genetic | 3 | 13.48 | 1.56E-03 | 2 | 3.90 | 0.09 |
Synthetic Sick | 0 | 0.00 | 1.00 | 24 | 19.98 | 3.06E-23 |
RNA - Signalling | ||||||
Positive | Negative | |||||
Dataset | Overlap | Enrichment | p-value | Overlap | Enrichment | p-value |
GO Process | 65 | 2.03 | 5.97E-09 | 162 | 2.25 | 7.63E-26 |
SGD Phenotype | 33 | 5.07 | 1.87E-14 | 88 | 6.02 | 7.13E-42 |
Positive Genetic | 16 | 71.81 | 1.19E-24 | 2 | 4.00 | 0.09 |
Synthetic Sick | 1 | 2.40 | 0.34 | 54 | 57.77 | 1.98E-74 |