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Table 1 Performance of GJE versus SVD

From: Symbolic flux analysis for genome-scale metabolic networks

Model Publ. Species Reactions Flux variables CPU time (s) ε SVD ×10-12 Condition number
    Orig. Open Dep. Indep. SVD GJE   
Example   118 129 156 118 39 0.02 0.03 0.003 15
iPS189 [15] 433 350 482 413 69 0.3 0.4 0.07 31000
iND750 [16] 1177 1266 1561 1162 399 6.2 8.0 6.37 68000
AraGEM [17] 1767 1625 2361 1720 641 19.7 34.2 12.65 3000
iAF1260 [18] 1972 2382 2773 1960 813 30.5 34.3 1.43 2800
Recon 1 [10] 3188 3742 4480 3169 1311 123.5 145.6 32.63 71000
  1. Kernel computation times for numerical SVD and symbolic GJE for the example yeast network given in Figure 3 and five genome-scale metabolic networks. All techniques are described in Methods. The condition number was calculated for Vindep from Equation (9). The inversion of Vindep is required to directly compare SVD results with the solution found from GJE. The difference between the results is given by ε SVD in Equation (11).