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Figure 2 | BMC Systems Biology

Figure 2

From: Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization

Figure 2

The expression perturbation patterns induced by BMP6 treatment in eight significant KEGG pathways. These pathways are consistently significantly differentially expressed or near so based on GAGE. The mean t-statistics from multiple one-on-one comparisons between the two sample conditions is used as overall perturbation magnitude for each pathway. Perturbation magnitude here is defined as the absolute value of both positive and negative gene expression changes without considering the actual perturbation direction. The dashed line indicates a t-statistic of 1.79, which roughly corresponds to p = 0.01 for 8-96 h or 0.001 for 10 d. Panel (a) and (b) are divided only for visual clarity.

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BMC Systems Biology

ISSN: 1752-0509

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