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Figure 6 | BMC Systems Biology

Figure 6

From: Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization

Figure 6

The expression perturbation patterns induced by BMP6 treatment in six significant experimental sets. Each of these experimental sets is significantly up or down regulated in at least one time point based on GAGE. (a) MYB targets, BAF57 down, BAF57 up; (b) IFNb up, VEGF up, IRS down. The mean t-statistics from multiple one-on-one comparisons between the two sample conditions is used as overall perturbation for each gene set. Different from KEGG pathways, perturbation direction is considered here. The dashed lines mark t = +/-1.78, which roughly correspond to p = 0.01 for 8-96 h or 0.001 for 10 d.

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BMC Systems Biology

ISSN: 1752-0509

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