Skip to main content

Table 1 Comparison of properties of reconstructed metabolic network for selected pathogens

From: Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction

Model

N.A.*

AbyMBEL891

i NJ661

i RR1083

i MO1056

i KF1028

Genome size

2.8 Mb

3.93 Mb

4.4 Mb

4.8 Mb

6.3 Mb

8.1 Mb

Included genes

758

650

661

1,083

1,056

1,028

Total reactions

1,497

891

939

1,087

883

859

Gene-associated reactions (% of total reactions)

1,278

713 (80%)

723 (77%)

1,018 (93.7%)

839 (95%)

832 (96.9%)

Non-gene-associated reactions

219

46

216

69

44

27

Transport reactions

146

130

93

230

133

102

Metabolites

1,431

778

828

744

760

834

  1. Properties of metabolic reconstruction of B. cenocepacia J2315 (iKF1028) were compared with other published metabolic reconstructions of pathogenic microbes, S. aureus N315 (2009) [18] (which is the improvement of the N315 reconstruction by Becker and Palsson 2005 [19], and Heinermann et al. 2005 [20]), A. baumannii AYE (AbyMBEL891) (2010) [21], M. tuberculosis H37Rv (iNJ661) (2007) [22], S. typhimurium LT2 (iRR1083) (2009) [23], and P. aeruginosa PAO1 (iMO1056) (2008) [24]. *: Not available for the reconstruction of S. aureus N315.