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Figure 4 | BMC Systems Biology

Figure 4

From: Large-scale analysis of expression signatures reveals hidden links among diverse cellular processes

Figure 4

Sub-network #4: Stem cell related gene sets and breast cancer prognosis predictors are linked. Nodes represent gene sets and edges represent significant overlaps. The size of the node indicates the number of genes in the gene set, which is also numerically labelled by the number at the end of each gene set name. The thickness of the edges is proportional to significance (-log10(FDR)). The labels of edges indicate the number of overlapping genes. The labels of edges indicate the number of overlapping genes. Red dashed edges represent repressive connections between "X" upregulated genes and "Y" downregulated genes. We observed overlaps between stem cell related expression signature and breast cancer prognosis predictors. Expression of some cell cycle related genes is shared between stem cells and invasive breast cancers.

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