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Figure 6 | BMC Systems Biology

Figure 6

From: Large-scale analysis of expression signatures reveals hidden links among diverse cellular processes

Figure 6

Expression of c-Myc target genes in B-lymphoma cells upon glutamine, leucine and glucose starvation as well as rapamycin treatment. Red and green denote higher and lower expression, respectively. Glutamine and leucine deficiencies, but not glucose deficiency, strongly downregulate many MYC target genes. The anticancer drug rapamycin has a similar effect on these genes, suggesting that rapamycin mimics amino acid starvation.

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