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Table 3 Kinetic constants of the tet operon reaction network.

From: Stochastic simulations of the tetracycline operon

kinetic constant

Ref.

kinetic constant

Ref.

kinetic constant

Ref.

kinetic constant

Ref.

k1 = 10+9

[31]h

k18 = 5.80·10-3

[31]

k35 = 30

[44]

k52 = 10+5

e

k2 = 10

[31]h

k19 = 0.10

[20]

k36 = 30

[44]a

k53 = 100

[44]

k3 = 10+8

[31]h

k20 = 4.80·10+5

[20]

k37 = 621

[8]b

k54 = 100

[44]a

k4 = 10-4

[31]h

k21 = 10-4

[20]

k38 = 7.23·10+6

[40, 63]h

k55 = 394

[64]b

k5 = 5.00·10+8

[16, 31]h

k22 = 2.40·10+5

[20]

k39 = 0.10

[63]h

k56 = 3.85·10-5

f

k6 = 10-4

[31]h

k23 = 2.00·10-4

[20]

k40 = 0.013

[63]

k57 = 3.85·10-5

f

k7 = 30

[31]h

k24 = 5.80·10-3

[31]

k41 = 30

[44]

k58 = 0.002

e

k8 = 0.10

[31]h

k25 = 0.10

[20]

k42 = 10+5

e

k59 = 0.002

e

k9 = 3.30·10-4

[65]

k26 = 4.8·10+4

[40, 63]h

k43 = 100

[44]

k60 = 2.67· 10-6

[43]

k10 = 4.80·10+5

[20]

k27 = 0.10

[63]h

k44 = 100

[44]a

k61 = 1

[13]c

k11 = 10-4

[20]

k28 = 0.013

[63]

k45 = 207

[8]b

k62 = 4.90·10-5

[21]d

k12 = 2.40·10+5

[20]

k29 = 30

[44]

k46 = 8.60·10+6

[19, 63]h

k63 = 10+8

g

k13 = 2.00·10-4

[20]

k30 = 30

[44]a

k47 = 0.10

[63]h

k64 = 10+8

[31]

k14 = 4.80·10+5

[20]

k31 = 621

[8]b

k48 = 0.013

[63]

k65 = 5.00·10+8

[16, 31]

k15 = 10-4

[20]

k32 = 9.10·10+5

[40, 63]h

k49 = 30

[44]

k66 = 0.10

[20]

k16 = 2.40·10+5

[20]

k33 = 0.10

[63]h

k50 = 30

[44]a

k67 = 0.10

[20]

k17 = 2.00·10-4

[20]

k34 = 0.013

[63]

k51 = 1182

[64]b

  
  1. Units on k: first order reactions: sec-1, second order reactions: M-1sec-1, third order reactions: M-2sec-1, fourth order reactions: M-3sec-1, fifth order reactions: M-4sec-1.
  2. a Scale parameter of the gamma distributed event (sec).
  3. b Shape parameter of the gamma distributed event.
  4. c k cat of Michaelis Menten kinetics.
  5. d K M of Michaelis Menten kinetics.
  6. e Rate adjusted to give 20 protein molecules per mRNA transcript.
  7. f Rate adjusted for 5 hours half life.
  8. g Rate adjusted for very fast reaction.
  9. h Rate calculated through equilibrium constant by assuming the forward and calculating the reverse rate.